GP100075: MUC1(126-149-Cys)-Tn(131,144) – hwacademy.id

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GP100075: MUC1(126-149-Cys)-Tn(131,144)

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Description

GP100075: MUC1(126-149-Cys)-Tn(131,144)C114H180N32O43S 2718. 9 MUC1 synthetic glycopeptide. Glycosylated Mucin 1 (MUC1) peptide fragment containing amino acid sequence Pro126Gly149 (24 AA in length) from the tandem repeat (TR) region of the MUC1 protein. The fragment contains tumor associated carbohydrate antigen (TACA), Tn antigen, O glycosylation ( GalNAc) at Thr131 and Thr144. The C terminus Cysteine (amide) allows for conjugation to maleimide functionalized carrier proteins. MUC1(126

IdoA-GlcNS Disodium Salt

/ A2 (Disialo 2

α-GalNAc-C4-COOCH3

C30H52N4O15S / 740

5 / A 4-methylumbelliferyl α-glycoside of a GlcNAcβ1-4Man disaccharide

Glycosylated Mucin-1 (MUC1) peptide fragment containing amino acid sequence Ala135–Arg150 (15 AA in length) from the tandem repeat (TR) region of the MUC1 protein

used to build proteoglycan-related glycopeptides

/ Fmoc-Ser(GlcNAcβ(1-3)GalNAc)-OH (Peracetate) / Core 3 O-Glycan on Serine

/ MUC1(126-149)-STn(144) / Mucin1

/ Fmoc-Thr(Neu5Acα(2-6)GalNAc)-OH (Peracetate

Fmoc-Ser(Glcα(1-4)Glc(Ac)7)-OH

C20H24N2O11 / 468

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