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Description

AG625005: α-D-Man-Ethyl-ThiolC8H16O6S 240. 27 An D mannose ligand equipped with a thiol functionalized linker through a short ethyl spacer. The thiol group can be reacted with other thiol modified substrates to form disulfide bonds, or reacted with maleimides to form stable thioether conjugates. This compound provides an D mannose building block for glycoconjugate synthesis and the construction of probes for mannose recognizing receptors and lectins, including the mannose

This compound enables the construction of hepatocyte-targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR)

61 / An α-D-N-acetylgalactosamine (GalNAcα) ligand on a threonine residue (Tn antigen

25 / A β-D-galactose ligand equipped with an azide-functionalized linker through a short propyl spacer

39 / A 4-nitrophenyl α-glycoside of kojibiose (Glcα1-2Glc)

α-D-GalNAc-Et-Azide

GalNAcα1-O-Ser) equipped with a biotin tag through an amide bond

The carboxylic acid can be activated to NHS

a non-reducing-end fragment relevant to the glycosaminoglycan-protein linkage region (the GAG tetrasaccharide linker GlcAβ1-3Galβ1-3Galβ1-4Xyl-O-Ser includes a xylose-glucuronic acid junction)

enabling its use in enzyme activity assays and in studies of sialic acid turnover

NaOH) to unmask the free acid for downstream activation to NHS

C8H15N3O5 / 233

protected form of the carboxylic acid that can be hydrolyzed under mild basic conditions (e

Exchange/Return Notes