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Description

GA621000: Fmoc-Ser(Man(Ac)4-α-D)-OHC32H35NO14 657. 62 An Fmoc protected L serine building block carrying an D mannose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as four acetate esters (Ac4), which keep the glycan inert during

Used as a fluorogenic substrate for sialidases (neuraminidases) with selectivity or preference for Neu5Gc-containing sialosides

Galβ(1-3)GalNAc-α-1-O-Threonine

2-Azidoethyl N-acetyllactosamine

4-Carboxybutyl α-D-rhamnopyranoside

N-(9-fluorenylmethoxycarbonyl)-O-(2-acetamido-3

22 / An α-L-rhamnose ligand equipped with an azide-functionalized linker through a short ethyl spacer

/ Blood Group A Trisaccharide-Biotin / Biotinyl Blood Group A Trisaccharide

α-L-Rha-Bu-CO2H

/ 4-Methylumbelliferyl α(GlcNAcβ(1-4)Man) / 4-MU-α(GlcNAcβ(1-4)Man)

β-D-LacNAc-C4-COOH

Fmoc-Ser(Galβ(1-4)Glc)-OH

64 / An Fmoc-protected L-asparagine building block carrying a β-D-glucose residue